ApoE4 Alzheimer's gene causes brain's blood vessels to leak, die

Common variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer's disease, but the gene's role in the disease has been unclear. Now, researchers funded by the National Institutes of Health have found that in mice, having the most risky variant of ApoE damages the blood vessels that feed the brain. Source: NIH/National Institute of Neurological Disorders and Stroke - Discipline: Neuroscience

ApoE4 Alzheimer's gene causes brain's blood vessels to leak, die

Common variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer's disease, but the gene's role in the disease has been unclear. Now, researchers funded ...

Wed 16 May 12 from Medical Xpress

Research provides new clues on how ApoE4 affects Alzheimer's risk, Wed 16 May 12 from Labspaces.net

NIH-funded research provides new clues on how ApoE4 affects Alzheimer's risk, Wed 16 May 12 from e! Science News

New clues on how ApoE4 affects Alzheimer's risk, Wed 16 May 12 from ScienceDaily

Alzheimer's Gene Causes Brain's Blood Vessels to Leak, Die

A well-known genetic risk factor for Alzheimer's disease triggers a cascade of signaling that ultimately results in leaky blood vessels in the brain, allowing toxic substances to pour into brain ...

Wed 16 May 12 from HealthCanal

Researcher Discovers Role of Gene Variant Associated With Alzheimer's Disease

By Leslie Ridgeway - A gene variant responsible for vascular damage to the brain is a promising new target for drug therapy to fight Alzheimer's disease and other neurodegenerative diseases, ...

Wed 16 May 12 from HealthCanal

Alzheimer's gene causes brain's blood vessels to leak toxins and die

ApoE4, a well-known genetic risk factor for Alzheimer's disease triggers a cascade of signaling that ultimately results in leaky blood vessels in the brain, allowing toxic substances to pour ...

Wed 16 May 12 from ScienceDaily

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