New Drugs Offer “Extraordinary Hope” In Skin Cancer Fight

Early trials saw reduction in tumours of those with malignant melanoma, the most aggressive form of the diseaseScientists held out hope today for those suffering from the most aggressive skin cancer, malignant melanoma, which has spread to other parts of the body, with news of a drug that may extend life.Early trials at the Massachusetts General hospital cancer centre in the United States showed a remarkable effect on the small number of patients with advanced cancer who were enrolled. In 80% of the patients, tumours were reduced in size. A few saw them disappear.The drug is targeted at the 40-60% of patients who have a specific mutation in the BRAF gene, which was discovered in 2002 at the Sanger Institute in the UK. The researchers, who report their findings in the New England Journal of Medicine, accept that the cancer will return in many cases, but say that the respite buys time."Metastatic melanoma has a devastating prognosis and is one of the top causes of cancer death in young patients," said Keith Fla

New Drugs Offer “Extraordinary Hope” In Skin Cancer Fight

A new drug may change the landscape of melanoma treatment, offering patients a treatment option that goes beyond anything previously used against the skin cancer, new research shows. Tests in ...

Thu 26 Aug 10 from Wired Science

Dramatic results for skin cancer pill

A pill for advanced skin cancer that targets patients with particular genetic make-up had dramatic results, scientists revealed.

Thu 26 Aug 10 from The Independent

New drug fights metastatic melanoma

Compound offers hope for about half of patients with advanced form of the skin cancer

Wed 25 Aug 10 from ScienceNews

New Drug Fights Metastatic Melanoma, Thu 26 Aug 10 from U.S. News

New Cancer Drug Gets Dramatic Results

Researchers call the experimental drug a major success for targeted cancer therapies. An experimental drug designed to block the effects of a genetic mutation often found in patients with malignant ...

Wed 25 Aug 10 from MIT Technology Review

Targeted drug leads to regression of metastatic melanoma with mutated BRAF gene

Use of an experimental targeted drug to treat metastatic melanoma tumors with a specific genetic signature was successful in more than 80 percent of patients in a phase 1 clinical trial. Results ...

Wed 25 Aug 10 from PhysOrg

Skin cancer drug offers new hope to patients

Early trials saw reduction in tumours of those with malignant melanoma, the most aggressive form of the diseaseScientists held out hope today for those suffering from the most aggressive skin ...

Wed 25 Aug 10 from Guardian.co.uk

In Early Trial, Targeted Therapy Fights Advanced Melanoma

By Amanda GardnerHealthDay Reporter WEDNESDAY, Aug. 25 (HealthDay News) — By probing deeper into the biological mechanisms that go awry in melanoma, scientists have come up with an experimental ...

Thu 26 Aug 10 from Health News

New Drug May Treat Advanced Melanoma

A new drug that fights tumors throughout the bodies of advanced melanoma patients points the way to powerful new treatments for many kinds of cancer.

Wed 25 Aug 10 from WebMD

Trial Therapy Improves Melanoma Survival

By Amanda GardnerHealthDay Reporter WEDNESDAY, Aug. 18 (HealthDay News) — An experimental drug for metastatic melanoma prolonged median survival from 6.4 months to 10 months, which, although ...

Thu 19 Aug 10 from Health News

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